Metoclopramide in the critically ill

Nutritional Assessment in Critically Ill Patients

Background: Malnutrition is an important factor in the survival of critically ill patients. The purpose of the present study was to assess the nutritional status of patients in the intensive care unit (ICU) on the days of admission and discharge via a detailed nutritional assessment. Methods: Totally, 125 patients were followed up from admission to discharge at 8ICUs in Shiraz, Iran. The patien...

probiotics in critically ill patients

Should we stop prescribing metoclopramide as a prokinetic drug in critically ill patients?

Regulatory agencies in North America and Europe recently re-evaluated the safety of metoclopramide. This re-evaluation resulted in recommendations and restrictions in order to minimise the risk of neurological and other adverse reactions associated with the use of metoclopramide. In the ICU, off-label prescription of metoclopramide is common. We have reviewed the evidence for safety, effectiven...

Still a Place for Metoclopramide as a Prokinetic Drug in Critically Ill Patients?

Recently, regulatory agencies in North America and Europe re-evaluated the safety of metoclopramide. This resulted in recommendations and restrictions in order to minimize the risk of neurological and other adverse reactions associated with the use of metoclopramide. The side effects in non-ICU patients are as follows: 1. Neurological adverse reactions, including extrapyramidal disorders, dyski...

Metformin Treatment in Hyperglycemic Critically Ill Patients: Another Challenge on the Control of Adverse Outcomes

New-onset hyperglycemia in patients admitted to intensive care units increases the risk of morbidity and mortality. Insulin resistance is frequently seen in the treatment of stress-induced hyperglycemia. Metformin, an oral anti-hyperglycemic agent, may introduce a new treatment protocol in critically ill patients with insulin-resistance hyperglycemia. Fifty-one non-diabetic traumatized patients...